Contents

HPLC Adsorbents
Silica
Particles
Particle size and distribution
Pore size, shape and distribution
Pore volume
Silica surface
Surface area
Surface chemistry
Silica - analyte interactions
Chemical modification of the silica surface
Types of bonds
Polymeric and monomeric bonding
Silica based "bonded phases"
Bonding density
Surface area after modification
Endcapping
The most popular bonded phases
C1, C4, C8, C18
Phenyl
CN
NH2
Diol
Chiral phases
Polymer based adsorbents